Julie R Ingelfinger Selected Research

Angiotensinogen

1/2021	Angiotensin II up-regulates sodium-glucose co-transporter 2 expression and SGLT2 inhibitor attenuates Ang II-induced hypertensive renal injury in mice.
10/2019	Tubular Deficiency of Heterogeneous Nuclear Ribonucleoprotein F Elevates Systolic Blood Pressure and Induces Glycosuria in Mice.
1/2017	Insulin Inhibits Nrf2 Gene Expression via Heterogeneous Nuclear Ribonucleoprotein F/K in Diabetic Mice.
7/2016	Overexpression of angiotensinogen downregulates aquaporin 1 expression via modulation of Nrf2-HO-1 pathway in renal proximal tubular cells of transgenic mice.
10/2015	Overexpression of heterogeneous nuclear ribonucleoprotein F stimulates renal Ace-2 gene expression and prevents TGF-β1-induced kidney injury in a mouse model of diabetes.
10/2014	Catalase overexpression prevents nuclear factor erythroid 2-related factor 2 stimulation of renal angiotensinogen gene expression, hypertension, and kidney injury in diabetic mice.
10/2012	Heterogeneous nuclear ribonucleoprotein F suppresses angiotensinogen gene expression and attenuates hypertension and kidney injury in diabetic mice.
6/2012	Selective, isolated proximal tubular angiotensinogen overexpression and salt-sensitive hypertension.
5/2012	Interferon-γ biphasically regulates angiotensinogen expression via a JAK-STAT pathway and suppressor of cytokine signaling 1 (SOCS1) in renal proximal tubular cells.
4/2012	Dual RAS blockade normalizes angiotensin-converting enzyme-2 expression and prevents hypertension and tubular apoptosis in Akita angiotensinogen-transgenic mice.

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Julie R Ingelfinger Research Topics

Disease

20	Hypertension (High Blood Pressure) 01/2021 - 01/2002
11	Fibrosis (Cirrhosis) 01/2021 - 02/2008
8	Hypertrophy 01/2018 - 02/2002
7	Albuminuria 04/2020 - 02/2008
7	Kidney Diseases (Kidney Disease) 04/2016 - 01/2009
7	Hypoxia (Hypoxemia) 04/2009 - 09/2003
6	Chronic Renal Insufficiency 01/2021 - 05/2006
6	Hyperglycemia 01/2021 - 12/2002
5	Diabetic Nephropathies (Diabetic Nephropathy) 01/2020 - 05/2006
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 04/2020 - 10/2015
3	Renal Hypertension 01/2018 - 10/2012
3	Type 2 Diabetes Mellitus (MODY) 01/2017 - 06/2008
3	Reperfusion Injury 04/2009 - 05/2002
3	Ischemia 04/2009 - 03/2002
3	Acute Kidney Injury (Acute Renal Failure) 06/2005 - 01/2003
2	Glucose Intolerance 01/2019 - 10/2006
2	Hemolytic-Uremic Syndrome 06/2013 - 02/2008
1	Segmental glomerulosclerosis 01/2022
1	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2021
1	Obesity 01/2021
1	Stroke (Strokes) 01/2021
1	Overweight 01/2021
1	Hyperaldosteronism (Conn Syndrome) 12/2020
1	Insulin Resistance 01/2020
1	Weight Loss (Weight Reduction) 01/2020
1	Glycosuria 10/2019
1	Pancreatitis 01/2019
1	Autosomal Dominant Polycystic Kidney (ADPKD) 11/2017
1	Congenital Abnormalities (Deformity) 11/2017
1	Disease Progression 10/2017
1	Weight Gain 03/2016
1	Isolated Systolic Hypertension 05/2015
1	Vesico-Ureteral Reflux (Vesicoureteral Reflux) 06/2014
1	Inflammation (Inflammations) 05/2012

Drug/Important Bio-Agent (IBA)

14	AngiotensinogenIBA 01/2021 - 12/2002
8	Proteins (Proteins, Gene)FDA Link 01/2020 - 02/2002
7	AlbuminsIBA 01/2021 - 03/2008
6	CreatinineIBA 01/2021 - 05/2015
6	Blood Glucose (Blood Sugar)IBA 01/2021 - 02/2008
6	Glucose (Dextrose)FDA LinkGeneric 10/2012 - 02/2002
5	Heterogeneous-Nuclear Ribonucleoproteins (Informatin)IBA 10/2019 - 10/2012
5	AngiotensinsIBA 01/2018 - 06/2010
5	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 02/2008
5	CatalaseIBA 10/2014 - 02/2008
4	Insulin (Novolin)FDA Link 04/2020 - 12/2002
4	Heterogeneous-Nuclear Ribonucleoprotein Group F-HIBA 01/2017 - 10/2012
3	Angiotensin IIIBA 01/2022 - 05/2004
3	Messenger RNA (mRNA)IBA 01/2021 - 02/2002
3	Sodium-Glucose Transporter 2 InhibitorsIBA 04/2020 - 01/2019
3	Streptozocin (Streptozotocin)FDA Link 01/2018 - 05/2006
3	Hydralazine (Apresoline)FDA LinkGeneric 07/2016 - 02/2008
3	Collagen Type IV (Type IV Collagen)IBA 03/2016 - 02/2008
3	Cyclin-Dependent Kinase Inhibitor p27IBA 10/2003 - 02/2002
2	SaltsIBA 01/2021 - 06/2012
2	CanagliflozinIBA 04/2020 - 10/2019
2	angiotensin I (1-7)IBA 01/2018 - 05/2015
2	Perindopril FDA LinkGeneric 07/2016 - 01/2009
2	Angiotensin-Converting Enzyme 2IBA 05/2015 - 01/2009
2	EnzymesIBA 06/2013 - 03/2008
2	Caspase 3 (Caspase-3)IBA 01/2009 - 02/2008
2	Transforming Growth Factor beta1 (TGF beta 1)IBA 01/2009 - 02/2002
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2008 - 05/2006
2	ElementsIBA 03/2008 - 05/2006
2	LuciferasesIBA 03/2008 - 05/2006
2	Shiga Toxin (Shigella Toxin)IBA 02/2008 - 06/2005
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 10/2005 - 01/2003
2	Type 1 Angiotensin ReceptorIBA 05/2004 - 01/2002
2	salicylhydroxamic acid (SHAM)IBA 05/2002 - 03/2002
1	semaglutideIBA 01/2021
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2021
1	Angiotensin Receptors (Angiotensin II Receptor)IBA 01/2021
1	ReninIBA 01/2021
1	finerenoneIBA 12/2020
1	NADPH Oxidase 4IBA 01/2018
1	Tolvaptan FDA Link 11/2017
1	Type 2 Angiotensin ReceptorIBA 11/2017
1	Biomarkers (Surrogate Marker)IBA 10/2017
1	Heterogeneous-Nuclear Ribonucleoprotein KIBA 01/2017
1	Losartan (Cozaar)FDA LinkGeneric 07/2016
1	Aquaporin 1IBA 07/2016
1	LipidsIBA 03/2016
1	Sodium-Glucose Transport ProteinsIBA 11/2015
1	AntioxidantsIBA 06/2013
1	Thromboplastin (Tissue Factor)IBA 06/2013
1	7-Ala-angiotensin (1-7)IBA 06/2013
1	InterferonsIBA 05/2012
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2012
1	Interleukin-6 (Interleukin 6)IBA 05/2012
1	CytokinesIBA 05/2012
1	Caspase 12IBA 06/2010
1	Lactoylglutathione LyaseIBA 04/2009
1	Extracellular Matrix ProteinsIBA 01/2009
1	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2009

Therapy/Procedure

6	Renal Replacement Therapy (Therapies, Renal Replacement) 04/2016 - 01/2016
5	Transplantation 04/2016 - 01/2016
3	Therapeutics 04/2020 - 04/2002
2	Renal Dialysis (Hemodialysis) 11/2003 - 01/2003
1	Glycemic Control 04/2020
1	Bariatric Surgery 01/2020
1	Antibiotic Prophylaxis 06/2014